Degenerative and regenerative pathways underlying Duchenne muscular dystrophy revealed by single-nucleus RNA sequencing

Duchenne muscular dystrophy (DMD) is a fatal muscle disorder characterized by cycles of degeneration and regeneration of multinucleated myofibers and pathological activation of a variety of other muscle-associated cell types. The extent to which different nuclei within the shared cytoplasm of a myof...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphovsmän: Chemello, Francesco, Wang, Zhaoning, Li, Hui, McAnally, John R., Liu, Ning, Bassel-Duby, Rhonda, Olson, Eric N.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2020
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7703557/
https://ncbi.nlm.nih.gov/pubmed/33148801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2018391117
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