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Correction of muscular dystrophies by CRISPR gene editing

Muscular dystrophies are debilitating disorders that result in progressive weakness and degeneration of skeletal muscle. Although the genetic mutations and clinical abnormalities of a variety of neuromuscular diseases are well known, no curative therapies have been developed to date. The advent of g...

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Bibliografski detalji
Izdano u:J Clin Invest
Glavni autori: Chemello, Francesco, Bassel-Duby, Rhonda, Olson, Eric N.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7259998/
https://ncbi.nlm.nih.gov/pubmed/32478678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI136873
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