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Correction of muscular dystrophies by CRISPR gene editing

Muscular dystrophies are debilitating disorders that result in progressive weakness and degeneration of skeletal muscle. Although the genetic mutations and clinical abnormalities of a variety of neuromuscular diseases are well known, no curative therapies have been developed to date. The advent of g...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Chemello, Francesco, Bassel-Duby, Rhonda, Olson, Eric N.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7259998/
https://ncbi.nlm.nih.gov/pubmed/32478678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI136873
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