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A facile method of mapping HIV-1 neutralizing epitopes using chemically masked cysteines and deep sequencing
Identification of specific epitopes targeted by neutralizing antibodies is essential to advance epitope-based vaccine design strategies. We report a facile methodology for rapid epitope mapping of neutralizing antibodies (NAbs) against HIV-1 Envelope (Env) at single-residue resolution, using Cys lab...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7703538/ https://ncbi.nlm.nih.gov/pubmed/33168755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2010256117 |
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