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Probing the Structure of the HIV-1 Envelope Trimer Using Aspartate Scanning Mutagenesis
HIV-1 envelope (Env) glycoprotein gp160 exists as a trimer of heterodimers on the viral surface. In most structures of the soluble ectodomain of trimeric HIV-1 envelope glycoprotein, the regions from 512 to 517 of the fusion peptide and from 547 to 568 of the N-heptad repeat are disordered. We used...
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| Publicado no: | J Virol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7565623/ https://ncbi.nlm.nih.gov/pubmed/32817217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01426-20 |
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