Inhibition of CAL27 Oral Squamous Carcinoma Cell by Targeting Hedgehog Pathway With Vismodegib or Itraconazole

Oral Squamous Cell Carcinoma (OSCC) presents an important challenge for the health systems worldwide. Thus, unraveling the biological mechanisms involved in OSCC pathogenesis is essential to the discovery of new drugs with anticancer potential. The Hedgehog (HH) pathway has shown promising results a...

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Vydáno v:Front Oncol
Hlavní autoři: Freitas, Raíza Dias, Dias, Rosane Borges, Vidal, Manuela Torres Andion, Valverde, Ludmila de Faro, Gomes Alves Costa, Rafaela, Damasceno, Andresa Karen Andrade, Sales, Caroline Brandi Schlaepfer, Siquara da Rocha, Leonardo de Oliveira, dos Reis, Mitermayer Galvão, Soares, Milena Botelho Pereira, Coletta, Ricardo Della, Pereira, Thiago Almeida, Bezerra, Daniel Pereira, Gurgel Rocha, Clarissa Araújo
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Oncology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7703359/
https://ncbi.nlm.nih.gov/pubmed/33312948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.563838
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