The JAK-STAT pathway regulates CD38 on myeloma cells in the bone marrow microenvironment: therapeutic implications

Anti-CD38 monoclonal antibody (MoAb) treatments including daratumumab (DARA) are effective therapies for both newly diagnosed and relapsed multiple myeloma (MM). In this study, we examined the soluble factors that modulate CD38 expression and are associated with sensitivity to DARA-mediated antibody...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Blood
Päätekijät: Ogiya, Daisuke, Liu, Jiye, Ohguchi, Hiroto, Kurata, Keiji, Samur, Mehmet K., Tai, Yu-Tzu, Adamia, Sophia, Ando, Kiyoshi, Hideshima, Teru, Anderson, Kenneth C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Hematology 2020
Aiheet:
Lymphoid Neoplasia
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7702477/
https://ncbi.nlm.nih.gov/pubmed/32844992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019004332
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