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Biochemical and transcript level differences between the three human phosphofructokinases show optimisation of each isoform for specific metabolic niches
6-Phosphofructokinase-1-kinase (PFK) tetramers catalyse the phosphorylation of fructose 6-phosphate (F6P) to fructose 1,6-bisphosphate (F16BP). Vertebrates have three PFK isoforms (PFK-M, PFK-L, and PFK-P). This study is the first to compare the kinetics, structures, and transcript levels of recombi...
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| Udgivet i: | Biochem J |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Portland Press Ltd.
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7702303/ https://ncbi.nlm.nih.gov/pubmed/33141153 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20200656 |
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