Hepatic Carbohydrate Response Element Binding Protein Activation Limits Nonalcoholic Fatty Liver Disease Development in a Mouse Model for Glycogen Storage Disease Type 1a

BACKGROUND AND AIMS: Glycogen storage disease (GSD) type 1a is an inborn error of metabolism caused by defective glucose‐6‐phosphatase catalytic subunit (G6PC) activity. Patients with GSD 1a exhibit severe hepatomegaly due to glycogen and triglyceride (TG) accumulation in the liver. We have shown th...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Hepatology
Prif Awduron: Lei, Yu, Hoogerland, Joanne A., Bloks, Vincent W., Bos, Trijnie, Bleeker, Aycha, Wolters, Henk, Wolters, Justina C., Hijmans, Brenda S., van Dijk, Theo H., Thomas, Rachel, van Weeghel, Michel, Mithieux, Gilles, Houtkooper, Riekelt H., de Bruin, Alain, Rajas, Fabienne, Kuipers, Folkert, Oosterveer, Maaike H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2020
Pynciau:
Original Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7702155/
https://ncbi.nlm.nih.gov/pubmed/32083759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.31198
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