Hepatic Farnesoid X-Receptor Isoforms α2 and α4 Differentially Modulate Bile Salt and Lipoprotein Metabolism in Mice

The nuclear receptor FXR acts as an intracellular bile salt sensor that regulates synthesis and transport of bile salts within their enterohepatic circulation. In addition, FXR is involved in control of a variety of crucial metabolic pathways. Four FXR splice variants are known, i.e. FXRα1-4. Althou...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Boesjes, Marije, Bloks, Vincent W., Hageman, Jurre, Bos, Trijnie, van Dijk, Theo H., Havinga, Rick, Wolters, Henk, Jonker, Johan W., Kuipers, Folkert, Groen, Albert K.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2014
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4266635/
https://ncbi.nlm.nih.gov/pubmed/25506828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115028
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