Inhibition of IRE1/JNK pathway in HK‐2 cells subjected to hypoxia‐reoxygenation attenuates mesangial cells‐derived extracellular matrix production

Endoplasmic reticulum (ER) stress and inflammatory responses play active roles in the transition of acute kidney injury (AKI) to chronic kidney disease (CKD). Inositol‐requiring enzyme 1 (IRE1) activates c‐Jun NH(2)‐terminal kinase (JNK) in ER stress. Tubular epithelial cells (TEC) are the main inju...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:J Cell Mol Med
Auteurs principaux: Liang, Yan, Liang, Lulu, Liu, Zhenjie, Wang, Yingzi, Dong, Xiubing, Qu, Lingyun, Gou, Rong, Wang, Yulin, Wang, Qian, Liu, Zhangsuo, Tang, Lin
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2020
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7701502/
https://ncbi.nlm.nih.gov/pubmed/33043579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15964
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires