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Inhibition of IRE1/JNK pathway in HK‐2 cells subjected to hypoxia‐reoxygenation attenuates mesangial cells‐derived extracellular matrix production
Endoplasmic reticulum (ER) stress and inflammatory responses play active roles in the transition of acute kidney injury (AKI) to chronic kidney disease (CKD). Inositol‐requiring enzyme 1 (IRE1) activates c‐Jun NH(2)‐terminal kinase (JNK) in ER stress. Tubular epithelial cells (TEC) are the main inju...
Gorde:
| Argitaratua izan da: | J Cell Mol Med |
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| Egile Nagusiak: | , , , , , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
John Wiley and Sons Inc.
2020
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7701502/ https://ncbi.nlm.nih.gov/pubmed/33043579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15964 |
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