Interleukin-17A Facilitates Chikungunya Virus Infection by Inhibiting IFN-α2 Expression

Interferons (IFNs) are the key components of innate immunity and are crucial for host defense against viral infections. Here, we report a novel role of interleukin-17A (IL-17A) in inhibiting IFN-α2 expression thus promoting chikungunya virus (CHIKV) infection. CHIKV infected IL-17A deficient (Il17a(...

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Dades bibliogràfiques
Publicat a:Front Immunol
Autors principals: Neupane, Biswas, Acharya, Dhiraj, Nazneen, Farzana, Gonzalez-Fernandez, Gabriel, Flynt, Alex Sutton, Bai, Fengwei
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7701120/
https://ncbi.nlm.nih.gov/pubmed/33304351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.588382
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