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Fragments of gD Protein as Inhibitors of BTLA/HVEM Complex Formation - Design, Synthesis, and Cellular Studies

One of the major current trends in cancer immunotherapy is the blockade of immune checkpoint proteins that negatively regulate the immune response. This has been achieved through antibodies blocking PD-1/PD-L1 and CTLA-4/CD80/CD86 interactions. Such antibodies have revolutionized oncological therapy...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Kuncewicz, Katarzyna, Battin, Claire, Sieradzan, Adam, Karczyńska, Agnieszka, Orlikowska, Marta, Wardowska, Anna, Pikuła, Michał, Steinberger, Peter, Rodziewicz-Motowidło, Sylwia, Spodzieja, Marta
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7700651/
https://ncbi.nlm.nih.gov/pubmed/33238640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21228876
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