Fragments of gD Protein as Inhibitors of BTLA/HVEM Complex Formation - Design, Synthesis, and Cellular Studies

One of the major current trends in cancer immunotherapy is the blockade of immune checkpoint proteins that negatively regulate the immune response. This has been achieved through antibodies blocking PD-1/PD-L1 and CTLA-4/CD80/CD86 interactions. Such antibodies have revolutionized oncological therapy...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Kuncewicz, Katarzyna, Battin, Claire, Sieradzan, Adam, Karczyńska, Agnieszka, Orlikowska, Marta, Wardowska, Anna, Pikuła, Michał, Steinberger, Peter, Rodziewicz-Motowidło, Sylwia, Spodzieja, Marta
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7700651/
https://ncbi.nlm.nih.gov/pubmed/33238640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21228876
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