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Influence of Cholesterol on the Orientation of the Farnesylated GTP-Bound KRas-4B Binding with Anionic Model Membranes

The Ras family of proteins is tethered to the inner leaflet of the cell membranes which plays an essential role in signal transduction pathways that promote cellular proliferation, survival, growth, and differentiation. KRas-4B, the most mutated Ras isoform in different cancers, has been under exten...

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Detalhes bibliográficos
Publicado no:Membranes (Basel)
Main Authors: Lu, Huixia, Martí, Jordi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7700388/
https://ncbi.nlm.nih.gov/pubmed/33266473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/membranes10110364
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