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Influence of Cholesterol on the Orientation of the Farnesylated GTP-Bound KRas-4B Binding with Anionic Model Membranes

The Ras family of proteins is tethered to the inner leaflet of the cell membranes which plays an essential role in signal transduction pathways that promote cellular proliferation, survival, growth, and differentiation. KRas-4B, the most mutated Ras isoform in different cancers, has been under exten...

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Vydáno v:Membranes (Basel)
Hlavní autoři: Lu, Huixia, Martí, Jordi
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7700388/
https://ncbi.nlm.nih.gov/pubmed/33266473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/membranes10110364
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