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Influence of Cholesterol on the Orientation of the Farnesylated GTP-Bound KRas-4B Binding with Anionic Model Membranes

The Ras family of proteins is tethered to the inner leaflet of the cell membranes which plays an essential role in signal transduction pathways that promote cellular proliferation, survival, growth, and differentiation. KRas-4B, the most mutated Ras isoform in different cancers, has been under exten...

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Detaylı Bibliyografya
Yayımlandı:Membranes (Basel)
Asıl Yazarlar: Lu, Huixia, Martí, Jordi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7700388/
https://ncbi.nlm.nih.gov/pubmed/33266473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/membranes10110364
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