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Therapeutic Potential of Heme Oxygenase-1 and Carbon Monoxide in Acute Organ Injury, Critical Illness, and Inflammatory Disorders

Heme oxygenase-1 (HO-1) is an inducible stress protein that catalyzes the oxidative conversion of heme to carbon monoxide (CO), iron, and biliverdin (BV), the latter of which is converted to bilirubin (BR) by biliverdin reductase. HO-1 has been implicated as a cytoprotectant in various models of acu...

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Detalhes bibliográficos
Publicado no:Antioxidants (Basel)
Autor principal: Ryter, Stefan W.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7699570/
https://ncbi.nlm.nih.gov/pubmed/33228260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox9111153
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