Therapeutic Potential of Heme Oxygenase-1/Carbon Monoxide in Lung Disease

Heme oxygenase (HO), a catabolic enzyme, provides the rate-limiting step in the oxidative breakdown of heme, to generate carbon monoxide (CO), iron, and biliverdin-IXα. Induction of the inducible form, HO-1, in tissues is generally regarded as a protective mechanism. Over the last decade, considerab...

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Main Authors: Constantin, Myrna, Choi, Alexander J. S., Cloonan, Suzanne M., Ryter, Stefan W.
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 2012
Assuntos:
Review Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296197/
https://ncbi.nlm.nih.gov/pubmed/22518295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/859235
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