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Heme Oxygenase-1/Carbon Monoxide: From Metabolism to Molecular Therapy
Heme oxygenase-1 (HO-1), a ubiquitous inducible stress-response protein, serves a major metabolic function in heme turnover. HO activity cleaves heme to form biliverdin-IXα, carbon monoxide (CO), and iron. Genetic experiments have revealed a central role for HO-1 in tissue homeostasis, protection ag...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Thoracic Society
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2742746/ https://ncbi.nlm.nih.gov/pubmed/19617398 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2009-0170TR |
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