High-Glucose-Induced Rab20 Upregulation Disrupts Gap Junction Intercellular Communication and Promotes Apoptosis in Retinal Endothelial and Müller Cells: Implications for Diabetic Retinopathy

To investigate whether high glucose (HG) alters Rab20 expression and compromises gap junction intercellular communication (GJIC) and cell survival, retinal cells were studied for altered intracellular trafficking of connexin 43 (Cx43). Retinal endothelial cells (RRECs) and retinal Müller cells (rMCs...

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Bibliographic Details
Published in:J Clin Med
Main Authors: Kim, Dongjoon, Lewis, Casey Stottrup, Sarthy, Vijay P., Roy, Sayon
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7699280/
https://ncbi.nlm.nih.gov/pubmed/33227912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm9113710
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