High Glucose Induces Mitochondrial Dysfunction in Retinal Müller Cells: Implications for Diabetic Retinopathy

PURPOSE: To investigate whether high glucose (HG) induces mitochondrial dysfunction and promotes apoptosis in retinal Müller cells. METHODS: Rat retinal Müller cells (rMC-1) grown in normal (N) or HG (30 mM glucose) medium for 7 days were subjected to MitoTracker Red staining to identify the mitocho...

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Vydáno v:Invest Ophthalmol Vis Sci
Hlavní autoři: Tien, Thomas, Zhang, Joyce, Muto, Tetsuya, Kim, Dongjoon, Sarthy, Vijay P., Roy, Sayon
Médium: Artigo
Jazyk:Inglês
Vydáno: The Association for Research in Vision and Ophthalmology 2017
Témata:
Retinal Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5460955/
https://ncbi.nlm.nih.gov/pubmed/28586916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.16-21355
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