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High-Glucose-Induced Rab20 Upregulation Disrupts Gap Junction Intercellular Communication and Promotes Apoptosis in Retinal Endothelial and Müller Cells: Implications for Diabetic Retinopathy

To investigate whether high glucose (HG) alters Rab20 expression and compromises gap junction intercellular communication (GJIC) and cell survival, retinal cells were studied for altered intracellular trafficking of connexin 43 (Cx43). Retinal endothelial cells (RRECs) and retinal Müller cells (rMCs...

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Publicado en:J Clin Med
Autores principales: Kim, Dongjoon, Lewis, Casey Stottrup, Sarthy, Vijay P., Roy, Sayon
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7699280/
https://ncbi.nlm.nih.gov/pubmed/33227912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm9113710
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