Age-Dependent Decline in Synaptic Mitochondrial Function Is Exacerbated in Vulnerable Brain Regions of Female 3xTg-AD Mice

Synaptic aging has been associated with neuronal circuit dysfunction and cognitive decline. Reduced mitochondrial function may be an early event that compromises synaptic integrity and neurotransmission in vulnerable brain regions during physiological and pathological aging. Thus, we aimed to measur...

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Bibliografiska uppgifter
I publikationen:Int J Mol Sci
Huvudupphovsmän: Espino de la Fuente-Muñoz, César, Rosas-Lemus, Mónica, Moreno-Castilla, Perla, Bermúdez-Rattoni, Federico, Uribe-Carvajal, Salvador, Arias, Clorinda
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2020
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7699171/
https://ncbi.nlm.nih.gov/pubmed/33227902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21228727
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