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Regional gene therapy with 3D printed scaffolds to heal critical sized bone defects in a rat model

The objective of the present study was to assess the ability of transduced rat bone marrow cells (RBMCs) that overexpress BMP-2 loaded on a three-dimensionally (3D) printed scaffold to heal a critical sized rat femoral defect. Tricalcium phosphate (TCP) scaffolds were 3D printed to fit a critical si...

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Detalhes bibliográficos
Publicado no:J Biomed Mater Res A
Main Authors: Alluri, Ram, Song, Xuan, Bougioukli, Sofia, Pannell, William, Vakhshori, Venus, Sugiyama, Osamu, Tang, Amy, Park, Sang-Hyun, Chen, Yong, Lieberman, Jay R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7699135/
https://ncbi.nlm.nih.gov/pubmed/31112357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbm.a.36727
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