Acid Sphingomyelinase Impacts Canonical Transient Receptor Potential Channels 6 (TRPC6) Activity in Primary Neuronal Systems

The acid sphingomyelinase (ASM)/ceramide system exhibits a crucial role in the pathology of major depressive disorder (MDD). ASM hydrolyzes the abundant membrane lipid sphingomyelin to ceramide that regulates the clustering of membrane proteins via microdomain and lipid raft organization. Several co...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cells
Päätekijät: Zeitler, Stefanie, Schumacher, Fabian, Monti, Juliana, Anni, Daniela, Guhathakurta, Debarpan, Kleuser, Burkhard, Friedland, Kristina, Fejtová, Anna, Kornhuber, Johannes, Rhein, Cosima
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2020
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7698877/
https://ncbi.nlm.nih.gov/pubmed/33218173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9112502
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