Treatment of Diabetic Neuropathy with A Novel PAR1-Targeting Molecule

Diabetic peripheral neuropathy (DPN) is a disabling common complication of diabetes mellitus (DM). Thrombin, a coagulation factor, is increased in DM and affects nerve function via its G-protein coupled protease activated receptor 1 (PAR1). Methods: A novel PAR1 modulator (PARIN5) was designed based...

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Publicado no:Biomolecules
Main Authors: Shavit-Stein, Efrat, Gofrit, Shany Guly, Gayster, Alexandra, Teldan, Yotam, Ron, Ariel, Abu Bandora, Eiman, Golderman, Valery, Gera, Orna, Harnof, Sagi, Chapman, Joab, Dori, Amir
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7698286/
https://ncbi.nlm.nih.gov/pubmed/33203057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10111552
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