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A Novel Highly Sensitive Method for Measuring Inflammatory Neural-Derived APC Activity in Glial Cell Lines, Mouse Brain and Human CSF

Background: Neural inflammation is linked to coagulation. Low levels of thrombin have a neuroprotective effect, mediated by activated protein C (APC). We describe a sensitive novel method for the measurement of APC activity at the low concentrations found in neural tissue. Methods: APC activity was...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Golderman, Valery, Gofrit, Shany G., Maggio, Nicola, Gera, Orna, Gerasimov, Alexandra, Laks, Dar, Chapman, Joab, Shavit-Stein, Efrat
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7177216/
https://ncbi.nlm.nih.gov/pubmed/32244492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21072422
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