Ischemic stroke in PAR1 KO mice: Decreased brain plasmin and thrombin activity along with decreased infarct volume

BACKGROUND: Ischemic stroke is a common and debilitating disease with limited treatment options. Protease activated receptor 1 (PAR1) is a fundamental cell signaling mediator in the central nervous system (CNS). It can be activated by many proteases including thrombin and plasmin, with various down-...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Shavit-Stein, Efrat, Mindel, Ekaterina, Gofrit, Shany Guly, Chapman, Joab, Maggio, Nicola
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2021
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7959388/
https://ncbi.nlm.nih.gov/pubmed/33720950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0248431
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