Loading...

Potent Quinoline-Containing Combretastatin A-4 Analogues: Design, Synthesis, Antiproliferative, and Anti-Tubulin Activity

A novel series of quinoline derivatives of combretastatin A-4 incorporating rigid hydrazone and a cyclic oxadiazole linkers were synthesized and have demonstrated potent tubulin polymerization inhibitory properties. Many of these novel derivatives have shown significant antiproliferative activities...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Pharmaceuticals (Basel)
Main Authors: Ibrahim, Tarek S., Hawwas, Mohamed M., Malebari, Azizah M., Taher, Ehab S., Omar, Abdelsattar M., O’Boyle, Niamh M., McLoughlin, Eavan, Abdel-Samii, Zakaria K., Elshaier, Yaseen A. M. M.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7698209/
https://ncbi.nlm.nih.gov/pubmed/33203182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph13110393
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!