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Design and Engineering of Deimmunized Vaccinia Viral Vectors

Vaccinia viral (VV) vectors are increasingly used in oncolytic virus therapy and vaccine development for cancer and infectious diseases. However, their effectiveness is hindered by the strong anti-viral immune response induced by the viral vector. In this review, we discuss the strategies to deimmun...

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Detalhes bibliográficos
Publicado no:Biomedicines
Main Authors: Song, Kevin, Viskovska, Mariya
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7697509/
https://ncbi.nlm.nih.gov/pubmed/33187060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines8110491
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