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Design and Engineering of Deimmunized Vaccinia Viral Vectors

Vaccinia viral (VV) vectors are increasingly used in oncolytic virus therapy and vaccine development for cancer and infectious diseases. However, their effectiveness is hindered by the strong anti-viral immune response induced by the viral vector. In this review, we discuss the strategies to deimmun...

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Podrobná bibliografie
Vydáno v:Biomedicines
Hlavní autoři: Song, Kevin, Viskovska, Mariya
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7697509/
https://ncbi.nlm.nih.gov/pubmed/33187060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines8110491
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