Cinnamides Target Leishmania amazonensis Arginase Selectively

Caffeic acid and related natural compounds were previously described as Leishmania amazonensis arginase (L-ARG) inhibitors, and against the whole parasite in vitro. In this study, we tested cinnamides that were previously synthesized to target human arginase. The compound caffeic acid phenethyl amid...

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Pubblicato in:Molecules
Autori principali: da Silva, Edson Roberto, Come, Júlio Abel Alfredo dos Santos Simone, Brogi, Simone, Calderone, Vincenzo, Chemi, Giulia, Campiani, Giuseppe, Oliveira, Trícia Maria Ferrreira de Sousa, Pham, Thanh-Nhat, Pudlo, Marc, Girard, Corine, Maquiaveli, Claudia do Carmo
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7696938/
https://ncbi.nlm.nih.gov/pubmed/33198198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25225271
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