Arginase expression modulates nitric oxide production in Leishmania (Leishmania) amazonensis

BACKGROUND: Arginase is an enzyme that converts L-arginine to urea and L-ornithine, an essential substrate for the polyamine pathway supporting Leishmania (Leishmania) amazonensis replication and its survival in the mammalian host. L-arginine is also the substrate of macrophage nitric oxide synthase...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Acuña, Stephanie Maia, Aoki, Juliana Ide, Laranjeira-Silva, Maria Fernanda, Zampieri, Ricardo Andrade, Fernandes, Juliane Cristina Ribeiro, Muxel, Sandra Marcia, Floeter-Winter, Lucile Maria
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5685479/
https://ncbi.nlm.nih.gov/pubmed/29135983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0187186
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