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Synthetic MIR143-3p Suppresses Cell Growth in Rhabdomyosarcoma Cells by Interrupting RAS Pathways Including PAX3–FOXO1

SIMPLE SUMMARY: Rhabdomyosarcoma (RMS) is a soft tissue sarcoma with embryonal (ERMS) and alveoral (ARMS) features, most frequently found in children. ARMS has the worse prognosis due to the formation of the chimeric PAX3–FOXO1 gene. New therapies are needed for the treatment of ARMS. The aim of thi...

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Publicado en:Cancers (Basel)
Autores principales: Sugito, Nobuhiko, Heishima, Kazuki, Ito, Yuko, Akao, Yukihiro
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7696565/
https://ncbi.nlm.nih.gov/pubmed/33182548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12113312
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