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Synthetic MIR143-3p Suppresses Cell Growth in Rhabdomyosarcoma Cells by Interrupting RAS Pathways Including PAX3–FOXO1

SIMPLE SUMMARY: Rhabdomyosarcoma (RMS) is a soft tissue sarcoma with embryonal (ERMS) and alveoral (ARMS) features, most frequently found in children. ARMS has the worse prognosis due to the formation of the chimeric PAX3–FOXO1 gene. New therapies are needed for the treatment of ARMS. The aim of thi...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Sugito, Nobuhiko, Heishima, Kazuki, Ito, Yuko, Akao, Yukihiro
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7696565/
https://ncbi.nlm.nih.gov/pubmed/33182548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12113312
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