Negative correlation of single-cell PAX3:FOXO1 expression with tumorigenicity in rhabdomyosarcoma

Rhabdomyosarcomas (RMS) are phenotypically and functionally heterogeneous. Both primary human RMS cultures and low-passage Myf6Cre,Pax3:Foxo1,p53 mouse RMS cell lines, which express the fusion oncoprotein Pax3:Foxo1 and lack the tumor suppressor Tp53 (Myf6Cre,Pax3:Foxo1,p53), exhibit marked heteroge...

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Bibliografski detalji
Izdano u:Life Sci Alliance
Glavni autori: Regina, Carla, Hamed, Ebrahem, Andrieux, Geoffroy, Angenendt, Sina, Schneider, Michaela, Ku, Manching, Follo, Marie, Wachtel, Marco, Ke, Eugene, Kikuchi, Ken, Henssen, Anton G, Schäfer, Beat W, Boerries, Melanie, Wagers, Amy J, Keller, Charles, Hettmer, Simone
Format: Artigo
Jezik:Inglês
Izdano: Life Science Alliance LLC 2021
Teme:
Research Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8321661/
https://ncbi.nlm.nih.gov/pubmed/34187933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.202001002
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