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In-Silico Identified New Natural Sortase A Inhibitors Disrupt S. aureus Biofilm Formation
Sortase A (SrtA) is a membrane-associated enzyme that anchors surface-exposed proteins to the cell wall envelope of Gram-positive bacteria such as Staphylococcus aureus. As SrtA is essential for Gram-positive bacterial pathogenesis but dispensable for microbial growth or viability, SrtA is considere...
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| Publicado no: | Int J Mol Sci |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7696255/ https://ncbi.nlm.nih.gov/pubmed/33202690 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21228601 |
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