Identification and engineering of 32 membered antifungal macrolactone notonesomycins

Notonesomycin A is a 32-membered bioactive glycosylated macrolactone known to be produced by Streptomyces aminophilus subsp. notonesogenes 647-AV1 and S. aminophilus DSM 40186. In a high throughput antifungal screening campaign, we identified an alternative notonesomycin A producing strain, Streptom...

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Detalhes bibliográficos
Publicado no:Microb Cell Fact
Main Authors: Goh, Falicia, Zhang, Mingzi M., Lim, Tian Ru, Low, Kia Ngee, Nge, Choy Eng, Heng, Elena, Yeo, Wan Lin, Sirota, Fernanda L., Crasta, Sharon, Tan, Zann, Ng, Veronica, Leong, Chung Yan, Zhang, Huibin, Lezhava, Alexander, Chen, Swaine L., Hoon, Shawn S., Eisenhaber, Frank, Eisenhaber, Birgit, Kanagasundaram, Yoganathan, Wong, Fong T., Ng, Siew Bee
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7081687/
https://ncbi.nlm.nih.gov/pubmed/32192516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-020-01328-x
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