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Gargantulide A, a Complex 52-Membered Macrolactone Showing Antibacterial Activity from Streptomyces sp

Gargantulide A (1), an extremely complex 52-membered macrolactone, was isolated from Streptomyces sp. A42983 and displayed moderate activity against MRSA. The planar structure of 1 was determined using 2D NMR, and its stereochemistry was partially established on the basis of NOESY correlations, J-ba...

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Detalhes bibliográficos
Publicado no:Org Lett
Main Authors: Rho, Jung-Rae, Subramaniam, Gurusamy, Choi, Hyukjae, Kim, Eun-Hee, Ng, Sok Peng, Yoganathan, K., Ng, Siewbee, Buss, Antony D., Butler, Mark S., Gerwick, William H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5125438/
https://ncbi.nlm.nih.gov/pubmed/25723256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.5b00068
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