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Elucidating the inhibition of peptidoglycan biosynthesis in Staphylococcus aureus by albocycline, a macrolactone isolated from Streptomyces maizeus

Antibiotic resistance is a serious threat to global public health, and methicillin-resistant Staphylococcus aureus (MRSA) is a poignant example. The macrolactone natural product albocycline, derived from various Streptomyces strains, was recently identified as a promising antibiotic candidate for th...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem
Main Authors: Liang, Hai, Zhou, Guangfeng, Ge, Yunhui, D’Ambrosio, Elizabeth A., Eidem, Tess M., Blanchard, Catlyn, Louka, Cindy, Chatare, Vijay K., Dunman, Paul M., Valentine, Ann M., Voelz, Vincent A., Grimes, Catherine L., Andrade, Rodrigo B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6008248/
https://ncbi.nlm.nih.gov/pubmed/29805074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2018.05.017
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