Hypoculoside, a sphingoid base-like compound from Acremonium disrupts the membrane integrity of yeast cells

We have isolated Hypoculoside, a new glycosidic amino alcohol lipid from the fungus Acremonium sp. F2434 belonging to the order Hypocreales and determined its structure by 2D-NMR (Nuclear Magnetic Resonance) spectroscopy. Hypoculoside has antifungal, antibacterial and cytotoxic activities. Homozygou...

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Publicado no:Sci Rep
Main Authors: Alfatah, Mohammad, Wong, Jin Huei, Nge, Choy Eng, Kong, Kiat Whye, Low, Kia Ngee, Leong, Chung Yan, Crasta, Sharon, Munusamy, Madhaiyan, Chang, Amanda Mun Leng, Hoon, Shawn, Ng, Siew Bee, Kanagasundaram, Yoganathan, Arumugam, Prakash
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345779/
https://ncbi.nlm.nih.gov/pubmed/30679518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-35979-z
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