Pivotal Role of Fatty Acid Synthase in c-MYC Driven Hepatocarcinogenesis

Hepatocellular carcinoma (HCC) is a deadly form of liver malignancy with limited treatment options. Amplification and/or overexpression of c-MYC is one of the most frequent genetic events in human HCC. The mammalian target of Rapamycin Complex 1 (mTORC1) is a major functional axis regulating various...

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Pubblicato in:Int J Mol Sci
Autori principali: Jia, Jiaoyuan, Che, Li, Cigliano, Antonio, Wang, Xue, Peitta, Graziella, Tao, Junyan, Zhong, Sheng, Ribback, Silvia, Evert, Matthias, Chen, Xin, Calvisi, Diego F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7696085/
https://ncbi.nlm.nih.gov/pubmed/33187130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21228467
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