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Hydrogen-Deuterium Exchange Mass Spectrometry: A Novel Structural Biology Approach to Structure, Dynamics and Interactions of Proteins and Their Complexes

Hydrogen/Deuterium eXchange Mass Spectrometry (HDX-MS) is a rapidly evolving technique for analyzing structural features and dynamic properties of proteins. It may stand alone or serve as a complementary method to cryo-electron-microscopy (EM) or other structural biology approaches. HDX-MS is capabl...

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Bibliographic Details
Published in:Life (Basel)
Main Authors: Ozohanics, Oliver, Ambrus, Attila
Format: Artigo
Language:Inglês
Published: MDPI 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7696067/
https://ncbi.nlm.nih.gov/pubmed/33203161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/life10110286
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