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Partial Sperm beta1 Integrin Subunit Deletion Proves Its Involvement in Mouse Gamete Adhesion/Fusion

We have previously shown, using antibodies, that the sperm alpha6beta1 integrin is involved in mouse gamete fusion in vitro. Here we report the conditional knockdown of the sperm Itgb1 gene. It induced a drastic failure of sperm fusogenic ability with sperm accumulation in the perivitelline space of...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Barraud-Lange, Virginie, Ialy-Radio, Côme, Chalas, Céline, Holtzmann, Isabelle, Wolf, Jean-Philippe, Barbaux, Sandrine, Ziyyat, Ahmed
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7696028/
https://ncbi.nlm.nih.gov/pubmed/33187358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21228494
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