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Partial Sperm beta1 Integrin Subunit Deletion Proves Its Involvement in Mouse Gamete Adhesion/Fusion

We have previously shown, using antibodies, that the sperm alpha6beta1 integrin is involved in mouse gamete fusion in vitro. Here we report the conditional knockdown of the sperm Itgb1 gene. It induced a drastic failure of sperm fusogenic ability with sperm accumulation in the perivitelline space of...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Barraud-Lange, Virginie, Ialy-Radio, Côme, Chalas, Céline, Holtzmann, Isabelle, Wolf, Jean-Philippe, Barbaux, Sandrine, Ziyyat, Ahmed
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7696028/
https://ncbi.nlm.nih.gov/pubmed/33187358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21228494
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