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New Insights on Molecular Mechanism of Hepatitis B Virus Covalently Closed Circular DNA Formation

The chronic factor of the Hepatitis B Virus (HBV), specifically the covalently closed circular DNA (cccDNA), is a highly stable and active viral episomal genome established in the livers of chronic hepatitis B patients as a constant source of disease. Being able to target and eliminate cccDNA is the...

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Pubblicato in:Cells
Autori principali: Marchetti, Alexander L., Guo, Haitao
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7694973/
https://ncbi.nlm.nih.gov/pubmed/33172220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9112430
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