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The Sulfilimine Analogue of Allicin, S-Allyl-S-(S-allyl)-N-Cyanosulfilimine, Is Antimicrobial and Reacts with Glutathione

When cells of garlic (Allium sativum) are disrupted by wounding, they produce the defense substance allicin (diallylthiosulfinate). Allicin is an efficient thiol trap and readily passes through cell membranes into the cytosol, where it behaves as a redox toxin by oxidizing the cellular glutathione (...

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Detalhes bibliográficos
Publicado no:Antioxidants (Basel)
Main Authors: Horn, Tobias, Bettray, Wolfgang, Noll, Ulrike, Krauskopf, Felix, Huang, Meng-Ruo, Bolm, Carsten, Slusarenko, Alan J., Gruhlke, Martin C. H.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7694261/
https://ncbi.nlm.nih.gov/pubmed/33158268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox9111086
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