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The Sulfilimine Analogue of Allicin, S-Allyl-S-(S-allyl)-N-Cyanosulfilimine, Is Antimicrobial and Reacts with Glutathione

When cells of garlic (Allium sativum) are disrupted by wounding, they produce the defense substance allicin (diallylthiosulfinate). Allicin is an efficient thiol trap and readily passes through cell membranes into the cytosol, where it behaves as a redox toxin by oxidizing the cellular glutathione (...

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Dades bibliogràfiques
Publicat a:Antioxidants (Basel)
Autors principals: Horn, Tobias, Bettray, Wolfgang, Noll, Ulrike, Krauskopf, Felix, Huang, Meng-Ruo, Bolm, Carsten, Slusarenko, Alan J., Gruhlke, Martin C. H.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7694261/
https://ncbi.nlm.nih.gov/pubmed/33158268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox9111086
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