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HIV-1 Uncoating and Nuclear Import Precede the Completion of Reverse Transcription in Cell Lines and in Primary Macrophages

An assembly of capsid proteins (CA) form the mature viral core enclosing the HIV-1 ribonucleoprotein complex. Discrepant findings have been reported regarding the cellular sites and the extent of core disassembly (uncoating) in infected cells. Here, we combined single-virus imaging and time-of-drug-...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Francis, Ashwanth C., Marin, Mariana, Prellberg, Mathew J., Palermino-Rowland, Kristina, Melikyan, Gregory B.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7693591/
https://ncbi.nlm.nih.gov/pubmed/33143125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12111234
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