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Single HIV-1 imaging reveals progression of infection through CA-dependent steps of docking at the nuclear pore, uncoating and nuclear transport

The HIV-1 core consists of capsid proteins (CA) surrounding viral genomic RNA. After virus-cell fusion, the core enters the cytoplasm and the capsid shell is lost through uncoating. CA loss precedes nuclear import and HIV integration into the host genome, but the timing and location of uncoating rem...

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Detalhes bibliográficos
Publicado no:Cell Host Microbe
Main Authors: Francis, A.C., Melikyan, G.B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5901770/
https://ncbi.nlm.nih.gov/pubmed/29649444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2018.03.009
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